Human Serum Albumin Mutant F502M GST TaggedSKU: P-200

General description: 

This reagent is not for sale. This specific albumin mutant is covered by a series of patent families owned and controlled by Albumedix A/S

Human serum albumin is the most abundant protein in human blood plasma. It is produced in the liver. Albumin constitutes about half of the blood serum protein. It is soluble and monomeric. Albumin transports hormones, fatty acids, and other compounds, buffers pH, and maintains osmotic pressure, among other functions. Albumin is synthesized in the liver as preproalbumin, which has an N-terminal peptide that is removed before the nascent protein is released from the rough endoplasmic reticulum. The product, proalbumin, is in turn cleaved in the Golgi vesicles to produce the secreted albumin.

The  albumin concentrations in serum is approximately 35 - 50 g/L (3.5 - 5.0 g/dL). It has a serum half-life of approximately 20 days, and a untagged molecular mass of 66.5 kDa.

About the scientist

Jan Terje Andersen

Associate Professor

The Laboratory for Adaptive Immunity and Homeostasis is studying the cellular processes and molecular interplay underlying the functions of the two most abundant proteins in the blood, albumin and IgG. By combining structural and biophysical approaches with cellular and in vivo studies, we use the insights to design novel albumin and IgG molecules with improved binding properties and cellular functions.