Human EndoGSKU: P-314

General description: 

Endonuclease G (EndoG) is an evolutionarily conserved, nuclear-encoded endonuclease reported to be involved in mtDNA replication, recombination, and degradation. On activation of apoptosis, EndoG is released from the mitochondrial intermembrane space and translocates to the cell nucleus to induce DNA fragmentation.

 

About the scientist

Adam Robertson

Group Leader

My research group has two principal research foci: (i) studying the cellular processes involving in the metabolism of the modified cytosine base – 5-hydroxymethylcytosine and (ii) the development of a continuous directed evolution platform that can be used in eukaryotic cells.