Rat Ly49i2SKU: P-260

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General description: 

Rat anti-rat Ly49i2 monoclonal antibody (clone STOK2)

Applications: Flow cytometry, Immunoprecipitation

Isotype: Rat IgG2a

Ly49i2 is an inhibitory C-type lectin like receptor for MHC class Ia (RT1-A1c) (http://www.ncbi.nlm.nih.gov/pubmed/12115624). The Ly49i2 receptor is expressed on a small population of NK and NKT cells in the high alloresponder rat strains: PVG, AO and LOU/C. It is not expressed in DA, F344, LEW or BN strains.

UniProt code: Q8K3G1

About the scientist

Lise Kveberg

Post doctoral fellow

The NK research group (NKRG) focuses on the biology and recognition mechanisms of Natural Killer (NK) cells, which constitute an important part of our innate immune defense against neoplastic and virally infected cells, and react with normal allogeneic cells. One main focus is on the characterization of several families of lectin-like receptors on NK cells and their roles in immune responses against diseased cells.

Group leader: John T. Vaage, Department head, Professor

ttp://www.ous-research.no/vaage/

http://www.med.uio.no/klinmed/personer/adm/lisek