human Neil3SKU: P-285

The Laboratory for Molecular Biology investigates basic biological processes associated with cellular responses to DNA damage including DNA repair pathways and mechanism for tolerance, scavenging and adaptation. Focus has been on the repair of endogenous DNA damage and mechanisms for removal of base damage to DNA. At the cellular and organismal level, the aim is to understand mechanisms for genome maintenance in mammalian as well as microbial cells and to develop new interventions for preventing cancer and neurological disease associated with genome instability caused by DNA damage.