Endonuclease G (EndoG) is an evolutionarily conserved, nuclear-encoded endonuclease reported to be involved in mtDNA replication, recombination, and degradation. On activation of apoptosis, EndoG is released from the mitochondrial intermembrane space and translocates to the cell nucleus to induce DNA fragmentation.
Human EndoGSKU: P-317
About the scientist
My research group has two principal research foci: (i) studying the cellular processes involving in the metabolism of the modified cytosine base – 5-hydroxymethylcytosine and (ii) the development of a continuous directed evolution platform that can be used in eukaryotic cells.