Rat NKR-P1FSKU: P-264

Link to publication: 
Go to publication
General description: 

Hamster anti-rat NKR-P1F monoclonal antibody (Clone ADA4).

Applications: Flow cytometry

Isotype: Armenian hamster IgG

Rat NKR-P1F is an activating C-type lectin-like receptor expressed on most NK and NKT cells and a subset of T cells. It is particularly high expression of NKR-P1F on intraepithelial cells in the intestinal mucosa, both on gamma delta T cells and alpha beta T cells. NKR-P1F has several ligands in the family of C-type lectin-related molecules (Clr)(http://www.ncbi.nlm.nih.gov/pubmed/21409442).

UniProt code: 

Q63378

About the scientist

Lise Kveberg

Post doctoral fellow

The NK research group (NKRG) focuses on the biology and recognition mechanisms of Natural Killer (NK) cells, which constitute an important part of our innate immune defense against neoplastic and virally infected cells, and react with normal allogeneic cells. One main focus is on the characterization of several families of lectin-like receptors on NK cells and their roles in immune responses against diseased cells.

Group leader: John T. Vaage, Department head, Professor

ttp://www.ous-research.no/vaage/

http://www.med.uio.no/klinmed/personer/adm/lisek