Rat MHC class ISKU: A-269

General description: 

Rat anti-rat MHC class I (Clone AAS6)

Applications: Flow cytometry

Isotype: IgG1

The binding specificity towards non-classical and classical MHC I molecules is dependent of MHC haplotype of the strain. AAS1 binds nonclassical RT1-CE molecules of the a, c, d, f, g, k, n haplotypes, and classical RT1-A1/A2 of the c haplotype, RT1-A1 of the n haplotype, and RT1-A of the q haplotype.

Other publication: http://www.ncbi.nlm.nih.gov/pubmed/21248147

UniProt codes: 

O62934_RAT

O62935_RAT

O78087_RAT

O62933_RAT

About the scientist

Lise Kveberg

Post doctoral fellow

The NK research group (NKRG) focuses on the biology and recognition mechanisms of Natural Killer (NK) cells, which constitute an important part of our innate immune defense against neoplastic and virally infected cells, and react with normal allogeneic cells. One main focus is on the characterization of several families of lectin-like receptors on NK cells and their roles in immune responses against diseased cells.

Group leader: John T. Vaage, Department head, Professor

ttp://www.ous-research.no/vaage/

http://www.med.uio.no/klinmed/personer/adm/lisek