Mouse anti-rat Ly49s3/i3/s4/i4 monoclonal antibody (DAR13)
Applications: Flow cytometry, Immunoprecipitation
Rat Ly49 receptors are a large family of C-type lectin-like receptors encoded in the NK gene complex on rat chromosome 4. The DAR13 monoclonal antibody stains subsets of NK and NKT cells (3-40% of NK cells and 10-20% of NKT cells) which also coexpress the majority of the other Ly49 molecules present in the animal. DAR13 binds to two pairs of structurally related receptors with opposing function; Ly49s3/i3 and Ly49s4/i4 (s: activating, i: inhibitory). The size of the subsets depends on the rat strain.